Serotonin-regulating medications such as SSRIs, antidepressants, or similar drugs can potentially inhibit or significantly reduce the effectiveness of these gummies. It's important to note that we are not medical professionals, so the information we provide is solely based on customer reports. The general issue arises from the fact that Selective Serotonin Reuptake Inhibitors (SSRIs) are designed to regulate the release of serotonin in the body. When an external form of serotonin is introduced, these medications are intended to balance it, preventing shifts between manic (increased) and depressive (decreased) phases. This applies to all similar medications designed to stabilize mood, including MAOIs, SNRIs, and TCAs.